A gene expression signature to predict disease progression for Hodgkin Lymphoma patients who achieve a complete metabolic response after 2 ABVD courses.

We employed a deep gene expression analysis searching for molecular determinants that could anticipate the risk of relapse among patients who achieve a complete metabolic response after 2 ABVD courses (iPET-). Kaplan Meyer curve analysis showed that Cluster 2 patients had a significative reduced PFS as compared to Cluster 1 ( I p i = 0.00043), supporting the prognostic relevance of these genes (Figure 1B). [Extracted from the article]