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HIGH RATE OF METABOLIC COMPLETE RESPONSE AFTER LOW DOSE RADIOTHERAPY AND OBINUTUZUMAB IN EARLY STAGE FOLLICULAR LYMPHOMA: INITIAL RESULTS OF THE GAZAI STUDY (GLA 2018‐3).
- Source :
- Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p218-220, 3p
- Publication Year :
- 2023
-
Abstract
- The prospective, multicentric phase II GAZAI study of the German Lymphoma Alliance (GLA) investigated the efficacy of low dose radiation therapy (2 × 2 Gy) in combination with the anti-CD20 antibody Obinutuzumab in early stage nodal FL. At week 18, metabolic CR (Deauville score (DS) <3) was seen in 46/53 patients (87%; one patient only had a CT without FDG-PET). B Introduction: b The FORT trial demonstrated a higher complete remission (CR) rate using 12 × 2 Gy compared to 2 × 2 Gy in Follicular Lymphoma (FL) (67% vs. 47%). [Extracted from the article]
- Subjects :
- FOLLICULAR lymphoma
IMMUNOGLOBULIN heavy chains
Subjects
Details
- Language :
- English
- ISSN :
- 02780232
- Volume :
- 41
- Database :
- Complementary Index
- Journal :
- Hematological Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 164230928
- Full Text :
- https://doi.org/10.1002/hon.3163_142