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Intravascular lithotripsy-assisted PCI for severely calcified coronary lesions: evaluating the impact on quality of life and outcomes.

Authors :
Buckley, Anthony J.
McCormick, John P.
Carey, James
Armstrong, Richard
Maree, Andrew
Hensey, Mark
O'Connor, Stephen
Murphy, Ross
Daly, Caroline
Cosgrave, John
Pearson, Ian
Source :
Irish Journal of Medical Science; Jun2023, Vol. 192 Issue 3, p1085-1090, 6p
Publication Year :
2023

Abstract

Background: Despite the increased uptake of intravascular lithotripsy (IVL) for treating severely calcified coronary lesions, there is limited patient-level data examining the effect of IVL on quality of life, symptomatology, and outcomes beyond 30 days. We sought to assess demographics, procedural characteristics, outcomes, and impact of IVL on patient-reported angina after a minimum of 6 months follow-up. Methods: A retrospective single-center study was conducted of patients treated with coronary IVL between January and October 2020. Baseline demographics were obtained from electronic patient records and SYNTAX scores were calculated from index coronary angiograms. Technical success and complications were assessed along with clinical outcomes, which included all-cause mortality, myocardial infarction (MI), target lesion revascularization (TLR), and MACE (composite of death, stroke, MI, and TLR). Canadian Cardiovascular Society (CCS) angina classification was assessed at virtual clinical follow-up. Results: Forty-seven consecutive patients were included. At a mean follow-up of 306 ± 74 days, the mean CCS angina score was reduced by 53% post-IVL-assisted PCI (2.9 vs 1.4, p < 0.001). Technical and procedural success were high (94% and 92%, respectively). One patient (2%) met the pre-specified criteria for in-hospital MACE and 4 (9%) met pre-specified MACE at follow-up, including 2 deaths and 2 TLR. Procedural complications included coronary dissection (11%) and coronary perforation (6%) and were managed either conservatively or with PCI. Conclusions: Coronary IVL is a safe and effective adjunctive therapy for treating heavily calcified coronary lesions. This cohort shows high procedural success and a significant reduction in CCS angina at follow-up. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00211265
Volume :
192
Issue :
3
Database :
Complementary Index
Journal :
Irish Journal of Medical Science
Publication Type :
Academic Journal
Accession number :
164176674
Full Text :
https://doi.org/10.1007/s11845-022-03077-9