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The correlation between severe complications and blood group types in COVID-19 patients; with possible role of T polyagglutination in promoting thrombotic tendencies.
- Source :
- AIMS Medical Science; 2023, Vol. 10 Issue 1, p1-13, 13p
- Publication Year :
- 2023
-
Abstract
- Introduction: Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still posing detrimental effects on people. An association between contracting COVID-19 and the ABO blood group type has been determined. However, factors that determine the severity of COVID-19 are not yet fully understood. Thus, the current study aimed to investigate whether the ABO blood group type has a role in the severity of complications due to COVID-19. Materials and methods: Eighty-Six ICU-admitted COVID-19 patients and 80 matched-healthy controls were recruited in the study from Baish general hospital, Saudi Arabia. ABO blood grouping, complete blood count (CBC), CBC-derived inflammatory markers, coagulation profile, D-Dimer and anti-T antigen were reported. Results: Our data showed that patients with blood groups O and B are more protective against severe complications from COVID-19, as compared to patients with blood groups A and AB. This could be partially attributed to the presence of anti-T in blood group A individuals, compared to non-blood group A. Conclusion: The current study reports an association between the ABO blood group and the susceptibility to severe complications from COVID-19, with a possible role of anti-T in driving the mechanism of the thrombotic tendency, as it was also correlated with an elevation in D-dimer levels. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 23751576
- Volume :
- 10
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- AIMS Medical Science
- Publication Type :
- Academic Journal
- Accession number :
- 164021828
- Full Text :
- https://doi.org/10.3934/medsci.2023001