Outstanding feasibility of spleen stiffness measurement by 100‐Hz vibration‐controlled transient elastography.

Patients with chronic liver disease with LSM < 7 kPa ( I n i = 967) had significantly lower SSM (18.6 ± 5.9 kPa) than patients with LSM > 15 kPa ( I n i = 127, 39.9 ± 15.1 kPa, I P i < 0.001; Fig. Similarly, patients with splenomegaly, which indicates potential portal hypertension in patients with chronic liver disease, had higher SSM than those without. Our data implied that this dedicated SSM would also be applicable for portal hypertension screening in patients with relatively mild liver disease who had normal spleen size. Keywords: chronic liver disease; ratio of interquartile range to median; spleen stiffness measurement; SSM@100 Hz; vibration-controlled transient elastography EN chronic liver disease ratio of interquartile range to median spleen stiffness measurement SSM@100 Hz vibration-controlled transient elastography 387 392 6 06/02/23 20230501 NES 230501 This novel spleen-dedicated FibroScan has high success rate and is easy to operate. [Extracted from the article]