A Self-Pumping Composite Dressing Improved Hypertrophic Scar Healing with Dual Therapy and Active-Fluid Transport.

Silicone gel sheeting (SGS) and pressure garment therapy (PGT) are the International Clinical Recommendations on Scar Management's (ICRSM) two principal non-invasive scar-healing procedures. This study created a new PGT-SGS composite (PGF-Biopor^®AB-based) via pre-strained screen printing. The Biopor^®AB hydrophobicity and nylon-hydrophilicity enabled self-pumping for PGT-SGS dual therapy and pressure-driven "warp insertions" mobility facilitates active-fluid transportation. Integrating both therapies in a single PGT-SGS composite achieved efficacy optimization, and the 3D channel structure allowed trauma-free active-fluid transport. The 3D channel topology enables smooth diffusional transport in active-fluid transport environments—and active "nylon absorbency" improved water uptake and enhanced permeability capabilities with sustainability achieved dynamic hydration. The sole use of PGF-Biopor^®AB composite in empirical trials verified dual therapy with trauma-free active-fluid transport with one-month efficacy, providing a new route for dual treatment and active scar management. [ABSTRACT FROM AUTHOR]