17-KETOSTEROIDS AND ARTERIOSCLEROSIS.

This paper reviews and evaluates medical literature reports and hospital records in an attempt to elucidate the apparent relationship between the activity of the suprarenal cortex, particularly 17-ketosteroids, and arteriosclerosis. The .suggestion obtained is that a shortage of 17-ketosteroids, especially dehydroepiandrosterone, seems to accompany, and possibly have causal significance in, cases of arteriosclerotic disease. Persons with an overabundance of 17-ketosteroids, and perhaps more specifically of dehydroepiandrosterone, may be relatively protected. Preliminary results of a treatment with dehydroepiandrosterone are presented in an addendum. [ABSTRACT FROM AUTHOR]