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In situ follicular neoplasm discovered as an enlarging pulmonary nodule complicated by pulmonary aspergillosis.

Authors :
Uchida, Tsuyoshi
Matsubara, Hirochika
Koizumi, Ryunosuke
Sasanuma, Harunobu
Sugimura, Aya
Onuki, Yuichiro
Nakajima, Hiroyuki
Oishi, Naoki
Source :
Thoracic Cancer; May2023, Vol. 14 Issue 15, p1401-1403, 3p
Publication Year :
2023

Abstract

In situ follicular B cell neoplasm, previously known as follicular lymphoma in situ, is a neoplastic proliferation of follicular lymphoma‐like B cells confined to the germinal centers. Herein, we report a case of a woman in her 70s who initially presented with several enlarged abdominal lymph nodes. Seven months later during follow‐up, a solitary pulmonary nodule was detected. As it was close to the hilum, lobectomy was performed. The intraoperative frozen section showed fibrosis and a collection of lymphocytes and macrophages. Therefore, the lymph nodes were sampled. Station 4 and 10 lymph nodes exhibited similar tumor cells and were immunohistochemically positive for CD10 and BCL2. Thus, the patient was diagnosed with in situ follicular neoplasm and is currently under observation. In situ follicular neoplasm is typically a slowly progressive neoplasm; however, it can present as a rapidly enlarging pulmonary nodule complicated by pulmonary aspergillosis. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17597706
Volume :
14
Issue :
15
Database :
Complementary Index
Journal :
Thoracic Cancer
Publication Type :
Academic Journal
Accession number :
163911500
Full Text :
https://doi.org/10.1111/1759-7714.14878