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The highly efficient protein crystallography beamline TLS 13B1 at the National Synchrotron Radiation Research Center.

Authors :
Chen, Yi‐Hui
Tseng, Chien‐Chang
Chou, Chung‐Kuang
Liu, Yi‐Chun
Chiang, Cheng‐Hung
Huang, Chen‐Ying
Chao, Chun‐Hsiung
Huang, Chun‐Hsiang
Source :
Journal of the Chinese Chemical Society; May2023, Vol. 70 Issue 5, p1219-1227, 9p
Publication Year :
2023

Abstract

Synchrotron protein crystallography (PX) is one of the most powerful and dominant tools for determining the three‐dimensional structures of biological macromolecules. At the National Synchrotron Radiation Research Center, TLS 13B1 is the first dedicated energy‐tunable and highly automated PX beamline for efficiently solving de novo protein structures in Taiwan and has been open for users since September 2005. With remote access, user support services, and annual PX training courses over 17 years, the number of user groups at TLS 13B1 has grown from 11 to 139. In total, 1,429 projects were supported, and 2090 experiments were hosted during 67,846 hr of beamtime. This paper describes the photon source, beamline components, experimental station equipment, beamline software, beamline application process, and results from our users. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00094536
Volume :
70
Issue :
5
Database :
Complementary Index
Journal :
Journal of the Chinese Chemical Society
Publication Type :
Academic Journal
Accession number :
163852337
Full Text :
https://doi.org/10.1002/jccs.202300057