Synthesis of nanosilver, organophosphate (C10H19O6PS2), and carbamate (CO2NH3) for anopheles larva control in malaria endemic area on Covid-19 pandemic.

Malaria is a national and global scale problem on Covid pandemic, with number of cases 516,272 (2020) in Indonesia and 7.9 million in Asia. Resistance use of insecticides, increase doses that harm non-target organisms. This research aims to determine LC90 in toxicity test of synthesis Nanosilver, Carbamate, and Organophosphate. It uses controlled post-treatment design, with total samples of 40 of treatment of Anopheles larvae in malaria endemic areas. LC90 calculation based on estimates and plotting the observed data with the y = ax + b formula. LC90 in synthesis of Nanosilver nitrate and Organophosphate is (0.5 mg/lt + 0.87mg/lt mg). LC90 in synthesis of Nanosilver nitrate and Organophosphate Carbamate are (0.5 mg/lt + 2.235 mg/lt). The absorption of silver nanoparticle into the body of larva Anopheles sp. occurs through the spiracles. Synthesis of Nanosilver and Organophosphate is more effective than Carbamate due to the nature of the Organophosphate and Carbamate materials which influenced by the size of the compounds. Synthesis Nanosilver nitrate (Ag₂NO₃) has LC90, 0.5 mg/lt + 0.87 mg/lt, which is effective for controlling larva of Anopheles sp. and eco-friendly material as it is better than Carbamate. [ABSTRACT FROM AUTHOR]