Back to Search
Start Over
Scale-free dynamics in the core-periphery topography and task alignment decline from conscious to unconscious states.
- Source :
- Communications Biology; 5/9/2023, Vol. 6 Issue 1, p1-15, 15p
- Publication Year :
- 2023
-
Abstract
- Scale-free physiological processes are ubiquitous in the human organism. Resting-state functional MRI studies observed the loss of scale-free dynamics under anesthesia. In contrast, the modulation of scale-free dynamics during task-related activity remains an open question. We investigate scale-free dynamics in the cerebral cortex's unimodal periphery and transmodal core topography in rest and task states during three conscious levels (awake, sedation, and anesthesia) complemented by computational modelling (Stuart-Landau model). The empirical findings demonstrate that the loss of the brain's intrinsic scale-free dynamics in the core-periphery topography during anesthesia, where pink noise transforms into white noise, disrupts the brain's neuronal alignment with the task's temporal structure. The computational model shows that the stimuli's scale-free dynamics, namely pink noise distinguishes from brown and white noise, also modulate task-related activity. Together, we provide evidence for two mechanisms of consciousness, temporo-spatial nestedness and alignment, suggested by the Temporo-Spatial Theory of Consciousness (TTC). Summary: Investigation of scale-free brain dynamics via rest-task modulation across awake, sedative, and anesthetic states of consciousness shows that brain dynamics lose alignment to the task's temporal structure in anesthesia as in wakefulness. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 23993642
- Volume :
- 6
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Communications Biology
- Publication Type :
- Academic Journal
- Accession number :
- 163725413
- Full Text :
- https://doi.org/10.1038/s42003-023-04879-y