Patent Issued for Tumor immunotherapy target and application thereof (USPTO 11634493).

On the contrary, the interaction between immune cells infiltrated by tumor microenvironment and tumor cells can promote and maintain the tumor cell sternness and has become a focus of studies because of its strong application prospects. "Tumor microenvironment factors can promote the tumor cell sternness to rely on the interaction between cells, and the tumor microenvironment is consisted of stromal infiltrating immune cells and other cells. In view of the fact that tumor-associated macrophages promote tumor progression, clearing tumor-associated macrophages and promoting the transformation of tumor-associated macrophages into immune activation have become potential methods for tumor treatment.". [Extracted from the article]