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Triterpene constituents from the fruits of Cyclocarya paliurus and their anti-HIV-1IIIB activity.
- Source :
- Natural Product Research; Jun2023, Vol. 37 Issue 11, p1787-1796, 10p
- Publication Year :
- 2023
-
Abstract
- Four new norceanothane-type triterpenes, cyclopalin A-D (1-4), and sixteen known compounds (5-20) were obtained from the fruits of Cyclocarya paliurus. Their structures were determined by spectroscopic data, experimental electronic circular dichroism (ECD) and X-ray single crystal analyses. All isolated compounds were assayed for their anti-HIV-1<subscript>IIIB</subscript> activity. Compound 18 exhibited potent anti-HIV-1<subscript>IIIB</subscript> activity with an EC<subscript>50</subscript> value of 1.32 μM (SI = 151.52). [ABSTRACT FROM AUTHOR]
- Subjects :
- TRITERPENES
CIRCULAR dichroism
SINGLE crystals
Subjects
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 37
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 163552554
- Full Text :
- https://doi.org/10.1080/14786419.2022.2120874