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Role of sarcopenia risk in predicting COVID-19 severity and length of hospital stay in older adults: a prospective cohort study.
- Source :
- British Journal of Nutrition; 6/14/2023, Vol. 129 Issue 11, p1888-1896, 9p
- Publication Year :
- 2023
-
Abstract
- Sarcopenia is more common in the elderly and causes adverse outcomes with increased morbidity and mortality. This prospective cohort study assessed the association of sarcopenia risk with the severity of COVID-19 at the time of admission and during hospitalisation and the length of hospital stay. Two hundred patients (aged ≥ 60 years) who were hospitalised for COVID-19 were enrolled using consecutive sampling between 29 December 2020 and 20 May 2021. The sarcopenia score of the patients was assessed using the Strength, Assistance in walking, Rising from a chair, Climbing stairs, and Falls questionnaire. The severity of COVID-19 was determined using the modified National Early Warning Score (m-NEWS) system for 2019 n-CoV-infected patients at admission (T1), day three (T2) and at discharge (T3). Data were analysed using SPSS, version 22 and STATA, version 14. Of the 165 patients included, thirty four (20·6 %) were at risk of sarcopenia. The length of hospital stay was slightly longer in patients with sarcopenia risk, but the difference was not significant (P = 0·600). The adjusted OR of respiratory rate (RR) > 20 /min at T1 for the sarcopenia risk group was 6·7-times higher than that for the non-sarcopenic group (P = 0·002). According to generalised estimating equations, after adjusting for confounding factors, the m-NEWS score was 5·6 units higher in patients at risk of sarcopenia (P < 0·001). Sarcopenia risk could exacerbate COVID-19 severity and increase RR at admission, as well as the need for oxygen therapy at discharge. [ABSTRACT FROM AUTHOR]
- Subjects :
- LENGTH of stay in hospitals
COVID-19
CONFIDENCE intervals
PREDICTIVE tests
SARCOPENIA
RESPIRATORY measurements
GERIATRIC assessment
SEVERITY of illness index
RISK assessment
COMPARATIVE studies
HOSPITAL care
QUESTIONNAIRES
DESCRIPTIVE statistics
RESEARCH funding
STATISTICAL sampling
DATA analysis software
ODDS ratio
LONGITUDINAL method
OLD age
Subjects
Details
- Language :
- English
- ISSN :
- 00071145
- Volume :
- 129
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- British Journal of Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 163546634
- Full Text :
- https://doi.org/10.1017/S000711452200215X