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Interventional Oncology and Immuno-Oncology: Current Challenges and Future Trends.

Authors :
Posa, Alessandro
Contegiacomo, Andrea
Ponziani, Francesca Romana
Punzi, Ernesto
Mazza, Giulia
Scrofani, Annarita
Pompili, Maurizio
Goldberg, Shraga Nahum
Natale, Luigi
Gasbarrini, Antonio
Sala, Evis
Iezzi, Roberto
Source :
International Journal of Molecular Sciences; Apr2023, Vol. 24 Issue 8, p7344, 14p
Publication Year :
2023

Abstract

Personalized cancer treatments help to deliver tailored and biologically driven therapies for cancer patients. Interventional oncology techniques are able to treat malignancies in a locoregional fashion, with a variety of mechanisms of action leading to tumor necrosis. Tumor destruction determines a great availability of tumor antigens that can be recognized by the immune system, potentially triggering an immune response. The advent of immunotherapy in cancer care, with the introduction of specific immune checkpoint inhibitors, has led to the investigation of the synergy of these drugs when used in combination with interventional oncology treatments. The aim of this paper is to review the most recent advances in the field of interventional oncology locoregional treatments and their interactions with immunotherapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16616596
Volume :
24
Issue :
8
Database :
Complementary Index
Journal :
International Journal of Molecular Sciences
Publication Type :
Academic Journal
Accession number :
163435245
Full Text :
https://doi.org/10.3390/ijms24087344