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Low-Dose Immunotherapy: Is It Just an Illusion?

Authors :
Meriggi, Fausto
Zaniboni, Alberto
Zaltieri, Anna
Source :
Biomedicines; Apr2023, Vol. 11 Issue 4, p1032, 6p
Publication Year :
2023

Abstract

The development and use of immunotherapy in the last decade have led to a drastic improvement in results in the onco-haematological field. This has implied, on the one hand, the need for clinicians to manage a new type of adverse event and, on the other hand, a significant increase in costs. However, emerging scientific evidence suggests that, as with other drugs in the recent past, the registry dosage can be drastically reduced for immunotherapies without penalizing their effectiveness. This would also lead to an important reduction in costs, expanding the audience of cancer patients who could access immunotherapy-based treatments. In this "Commentary", we analyze the available evidence of pharmacokinetics and pharmacodynamics and the most recent literature in favor of low-dose immunotherapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22279059
Volume :
11
Issue :
4
Database :
Complementary Index
Journal :
Biomedicines
Publication Type :
Academic Journal
Accession number :
163390197
Full Text :
https://doi.org/10.3390/biomedicines11041032