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ETV4 Mediated TumorāAssociated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023).
- Source :
- Advanced Science; 4/14/2023, Vol. 10 Issue 11, p1-1, 1p
- Publication Year :
- 2023
-
Abstract
- ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023) B Tumor-Associated Neutrophil b In article number 2205613, Xu Chen, Tianxin Lin, and co-workers reveal a novel mechanism of tumor-associated neutrophil (TANs) in lymph node (LN)-metastatic bladder cancer. ETS variant transcription factor (ETV4) enhances bladder cancer (BCa) cells-derived chemokine C-X-C motif ligand (CXCL)1/8 to recruit TANs, leading to the increase of vascular endothelial growth factor A (VEGFA) and matrix metalloproteinase-9 (MMP9), and then facilitating lymphangiogenesis and LN metastasis of bladder cancer. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 21983844
- Volume :
- 10
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Advanced Science
- Publication Type :
- Academic Journal
- Accession number :
- 163112505
- Full Text :
- https://doi.org/10.1002/advs.202370065