An IoT-Fog-Cloud Integrated Framework for Real-Time Remote Cardiovascular Disease Diagnosis.

Recently, it has proven difficult to make an immediate remote diagnosis of any coronary illness, including heart disease, diabetes, etc. The drawbacks of cloud computing infrastructures, such as excessive latency, bandwidth, energy consumption, security, and privacy concerns, have lately been addressed by Fog computing with IoT applications. In this study, an IoT-Fog-Cloud integrated system, called a Fog-empowered framework for real-time analysis in heart patients using ENsemble Deep learning (FRIEND), has been introduced that can instantaneously facilitate remote diagnosis of heart patients. The proposed system was trained on the combined dataset of Long-Beach, Cleveland, Switzerland, and Hungarian heart disease datasets. We first tested the model with eight basic ML approaches, including the decision tree, logistic regression, random forest, naive Bayes, k-nearest neighbors, support vector machine, AdaBoost, and XGBoost approaches, and then applied ensemble methods including bagging classifiers, weighted averaging, and soft and hard voting to achieve enhanced outcomes and a deep neural network, a deep learning approach, with the ensemble methods. These models were validated using 16 performance and 9 network parameters to justify this work. The accuracy, PPV, TPR, TNR, and F1 scores of the experiments reached 94.27%, 97.59%, 96.09%, 75.44%, and 96.83%, respectively, which were comparatively higher when the deep neural network was assembled with bagging and hard-voting classifiers. The user-friendliness and the inclusion of Fog computing principles, instantaneous remote cardiac patient diagnosis, low latency, and low energy consumption, etc., are advantages confirmed according to the achieved experimental results. [ABSTRACT FROM AUTHOR]