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Correction: Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity.

Authors :
Lee, Ho Jin
Pham, Phuong Chi
Hyun, Seung Yeob
Baek, Byungyeob
Kim, Byungjin
Kim, Yunha
Min, Hye-Young
Lee, Jeeyeon
Lee, Ho-Young
Source :
Molecular Cancer; 3/15/2023, Vol. 22 Issue 1, p1-2, 2p
Publication Year :
2023

Abstract

The expression of total and phosphorylated IGF1R and Src was determined by Western blot analysis. f A549 cells were treated with linsitinib (1 M) or dasatinib (100 nM) for 1 day. The immunoprecipitants were further subjected to Western blot analysis using anti-pTyr, anti-IGF1R, and anti-IR antibodies. e R- cells were treated with LL28 (0.1 and 1 M) for 8 h. The expression of total and phosphorylated IGF1R and Src was evaluated by Western blot analysis. g A549, H1299, and H460 cells were treated with LL28 (0.1 M) for 1, 3, and 5 days. [Extracted from the article]

Details

Language :
English
ISSN :
14764598
Volume :
22
Issue :
1
Database :
Complementary Index
Journal :
Molecular Cancer
Publication Type :
Academic Journal
Accession number :
162514885
Full Text :
https://doi.org/10.1186/s12943-023-01754-6