Back to Search
Start Over
Correction: Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity.
- Source :
- Molecular Cancer; 3/15/2023, Vol. 22 Issue 1, p1-2, 2p
- Publication Year :
- 2023
-
Abstract
- The expression of total and phosphorylated IGF1R and Src was determined by Western blot analysis. f A549 cells were treated with linsitinib (1 M) or dasatinib (100 nM) for 1 day. The immunoprecipitants were further subjected to Western blot analysis using anti-pTyr, anti-IGF1R, and anti-IR antibodies. e R- cells were treated with LL28 (0.1 and 1 M) for 8 h. The expression of total and phosphorylated IGF1R and Src was evaluated by Western blot analysis. g A549, H1299, and H460 cells were treated with LL28 (0.1 M) for 1, 3, and 5 days. [Extracted from the article]
- Subjects :
- ANTINEOPLASTIC agents
DASATINIB
WESTERN immunoblotting
Subjects
Details
- Language :
- English
- ISSN :
- 14764598
- Volume :
- 22
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Molecular Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 162514885
- Full Text :
- https://doi.org/10.1186/s12943-023-01754-6