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Prevalence and Risk Factors for Obstructive Sleep Apnea Syndrome Among Children and Adolescents with Cleft lip and Palate: A Survey Study in Hong Kong.
- Source :
- Cleft Palate Craniofacial Journal; Apr2023, Vol. 60 Issue 4, p421-429, 9p
- Publication Year :
- 2023
-
Abstract
- Objective: To investigate the prevalence of obstructive sleep apnea syndrome (OSAS) risk and related risk factors among children and adolescents of Hong Kong with cleft lip and/or palate (CL/P). Design: Retrospective survey study adopting three questionnaires, obstructive sleep apnea-18 (OSA-18), pediatric sleep questionnaire-22 (PSQ-22), and modified Epworth Sleepiness Scale (ESS). Settings: Multicenter study in two public hospitals. Patients: A total of 351 Chinese children and adolescents with non-syndromic CL/P (6-18-year-old, 57% males) visited between September 2017 and November 2019, with primary palatal repair surgery done before 3-year-old. Main Outcome Measure: Positive OSAS risk was determined based on cut-off ≥60 for OSA-18, ≥8 for PSQ-22, and >8 for ESS. Age, sex, overweight presence, cleft type, embryonic secondary palate involvement, palatal repair surgery, palatal revision surgery, and orthodontic treatment were analyzed as possible risk factors. Results: A total of 9.5% of patients had positive OSAS risk based on OSA-18, 13.6% based on PSQ-22, and 13.2% according to ESS. A higher prevalence of patients with positive OSAS risk was of younger age (OSA-18, p =.034), had cleft involving embryonic secondary palate (PSQ-22, p =.009), and history of fixed orthodontic treatment (ESS, p =.002). The regression model identified only involvement of embryonic secondary palate as a risk factor (PSQ-22, odds ratio = 3.7, p =.015). Conclusions: OSAS risk among children and adolescents of Hong Kong with CL/P was 9.5% to 13.6%. Patients at higher risk were those with cleft involving embryonic secondary palate. OSAS risk assessment may be influenced by different aspects of the disease spectrum, and a multimodal approach should be considered for such assessment. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10556656
- Volume :
- 60
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Cleft Palate Craniofacial Journal
- Publication Type :
- Academic Journal
- Accession number :
- 162431610
- Full Text :
- https://doi.org/10.1177/10556656211068306