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Respiration-timing-dependent changes in activation of neural substrates during cognitive processes.

Authors :
Nakamura, Nozomu H
Fukunaga, Masaki
Yamamoto, Tetsuya
Sadato, Norihiro
Oku, Yoshitaka
Source :
Cerebral Cortex Communications; 2022, Vol. 3 Issue 4, p1-12, 12p
Publication Year :
2022

Abstract

We previously showed that cognitive performance declines when the retrieval process spans an expiratory-to-inspiratory (EI) phase transition (an onset of inspiration). To identify the neural underpinning of this phenomenon, we conducted functional magnetic resonance imaging (fMRI) while participants performed a delayed matching-to-sample (DMTS) recognition memory task with a short delay. Respiration during the task was monitored using a nasal cannula. Behavioral data replicated the decline in memory performance specific to the EI transition during the retrieval process, while an extensive array of frontoparietal regions were activated during the encoding, delay, and retrieval processes of the task. Within these regions, when the retrieval process spanned the EI transition, activation was reduced in the anterior cluster of the right temporoparietal junction (TPJa, compared to cases when the retrieval process spanned the inspiratory-to-expiratory phase transition) and the left and right middle frontal gyrus, dorsomedial prefrontal cortex, and somatosensory areas (compared to cases when the retrieval process did not span any phase transition). These results in task-related activity may represent respiratory interference specifically in information manipulation rather than memory storage. Our findings demonstrate a cortical-level effect of respiratory phases on cognitive processes and highlight the importance of the timing of breathing for successful performance. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
26327376
Volume :
3
Issue :
4
Database :
Complementary Index
Journal :
Cerebral Cortex Communications
Publication Type :
Academic Journal
Accession number :
162356389
Full Text :
https://doi.org/10.1093/texcom/tgac038