Green fabrication of silver nanoparticles from Salvia species extracts: characterization and anticancer activities against A549 human lung cancer cell line.

Green synthesis of Ag NPs has been increasing for diverse applications in recent years. The present study proposed the synthesis of Ag NPs using mint family plants of Salvia coccinea, Salvia leucantha and Salvia splendens and their efficacy against cancer cells. The green synthesized silver nanoparticles were characterized and confirmed using UV-spectrometer and X-ray powder diffraction. The observed peaks in FTIR showed Phyto-functional groups and the stretch of bonds that corresponds to AgNPs synthesis. Scanning Electron Microscope morphologically identified the structure of the silver nanoparticles. The synthesized nanoparticles showed significant anticancer activity against the A549 human lung cancer cells (HLCCs). Moreover, it's also demonstrated for the first time the anticancer activity of silver nanoparticles from three Salvia plant species against A549 HLCCs. The results demonstrate the anticancer activities of AgNPs, suggesting that they may act as potential beneficial molecules in A549 HLCCs chemoprevention and chemotherapy, especially for early-stage intervention. [ABSTRACT FROM AUTHOR]