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Longitudinal Course of Sleep Disturbance and Relationship With Itch in Adult Atopic Dermatitis in Clinical Practice.
- Source :
- Dermatitis (Mary Ann Liebert, Inc.); Jan/Feb2023, Vol. 34 Issue 1, p42-50, 9p
- Publication Year :
- 2023
-
Abstract
- Background: Sleep disturbance (SD) is common in atopic dermatitis (AD). Weexamined the longitudinal course ofSD and relationship with itch in AD patients. Methods: A prospective, dermatology practice--based study was performed (N = 1295) where patients were assessed at baseline and follow-up visits. Results: At baseline, 16.9% of the patients had severe SD based on Patient-Reported Outcomes Information System (PROMIS) SD T scores, 19.1% had difficulty falling asleep, 22.9% had difficulty staying asleep, and 34.2% had SD from AD. A total of 31.4% of the patients with difficulty staying asleep at baseline experienced persistent difficulties (for 3 followups or more). Only 17.7% with baseline difficulty falling asleep had persistent disturbance. Despite significant fluctuation in sleep scores, SD generally improved over time. Of the patients facing baseline SD from AD, 31.5% experienced SD at the first visit, and only 12.3% experienced persistent SD at the second follow-up visit. Predictors of increased PROMIS sleep-related impairment T scores over time included baseline PROMIS sleep-related impairment T scores (0.74 [0.68--0.80]), having 3 to 6 nights of itch (2.22 [0.85--3.59]), and severe/very severe AD (4.40 [2.60--6.20]). Conclusions: A significant proportion of adult AD patients, particularly those with moderate-severe AD and frequent itch, had baseline SD. Although sleep scores generally improved over time, many patients experienced a fluctuating or persistent course. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17103568
- Volume :
- 34
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Dermatitis (Mary Ann Liebert, Inc.)
- Publication Type :
- Academic Journal
- Accession number :
- 161775074
- Full Text :
- https://doi.org/10.1089/derm.0000000000000859