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Cardiopulmonary, Functional, Cognitive and Mental Health Outcomes Post-COVID-19, Across the Range of Severity of Acute Illness, in a Physically Active, Working-Age Population.
- Source :
- Sports Medicine - Open; 2/2/2023, Vol. 9 Issue 1, p1-14, 14p
- Publication Year :
- 2023
-
Abstract
- Background: The COVID-19 pandemic has led to significant morbidity and mortality, with the former impacting and limiting individuals requiring high physical fitness, including sportspeople and emergency services. Methods: Observational cohort study of 4 groups: hospitalised, community illness with on-going symptoms (community-symptomatic), community illness now recovered (community-recovered) and comparison. A total of 113 participants (aged 39 ± 9, 86% male) were recruited: hospitalised (n = 35), community-symptomatic (n = 34), community-recovered (n = 18) and comparison (n = 26), approximately five months following acute illness. Participant outcome measures included cardiopulmonary imaging, submaximal and maximal exercise testing, pulmonary function, cognitive assessment, blood tests and questionnaires on mental health and function. Results: Hospitalised and community-symptomatic groups were older (43 ± 9 and 37 ± 10, P = 0.003), with a higher body mass index (31 ± 4 and 29 ± 4, P < 0.001), and had worse mental health (anxiety, depression and post-traumatic stress), fatigue and quality of life scores. Hospitalised and community-symptomatic participants performed less well on sub-maximal and maximal exercise testing. Hospitalised individuals had impaired ventilatory efficiency (higher VE/V̇CO<subscript>2</subscript> slope, 29.6 ± 5.1, P < 0.001), achieved less work at anaerobic threshold (70 ± 15, P < 0.001) and peak (231 ± 35, P < 0.001), and had a reduced forced vital capacity (4.7 ± 0.9, P = 0.004). Clinically significant abnormal cardiopulmonary imaging findings were present in 6% of hospitalised participants. Community-recovered individuals had no significant differences in outcomes to the comparison group. Conclusion: Symptomatically recovered individuals who suffered mild-moderate acute COVID-19 do not differ from an age-, sex- and job-role-matched comparison population five months post-illness. Individuals who were hospitalised or continue to suffer symptoms may require a specific comprehensive assessment prior to return to full physical activity. [ABSTRACT FROM AUTHOR]
- Subjects :
- COGNITION disorders
EXERCISE tests
HOSPITAL emergency services
COVID-19
SCIENTIFIC observation
LUNG diseases
FUNCTIONAL status
CROSS-sectional method
CARDIOVASCULAR diseases
MENTAL health
PHYSICAL fitness
ATHLETES
POST-traumatic stress disorder
SEVERITY of illness index
COMPARATIVE studies
SOCIOECONOMIC factors
HOSPITAL care
QUESTIONNAIRES
MENTAL depression
QUALITY of life
DESCRIPTIVE statistics
RESEARCH funding
BLOOD testing
BODY mass index
ANXIETY
FATIGUE (Physiology)
COVID-19 pandemic
ACUTE diseases
LONGITUDINAL method
Subjects
Details
- Language :
- English
- ISSN :
- 21991170
- Volume :
- 9
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Sports Medicine - Open
- Publication Type :
- Academic Journal
- Accession number :
- 161656498
- Full Text :
- https://doi.org/10.1186/s40798-023-00552-0