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Insights from a rare myeloproliferative neoplasm with coexisting BCR‐ABL1 fusion gene, CALR, and TET2 mutations treated with nilotinib and ruxolitinib.

Authors :
Huo, Li
Xie, Jundan
Wang, Qian
Shen, Hongjie
Ding, Zixuan
Wen, Lijun
Zeng, Zhao
Xu, Yi
Ruan, Changgeng
Chen, Suning
Xue, Mengxing
Source :
Clinical Case Reports; Jan2023, Vol. 11 Issue 1, p1-7, 7p
Publication Year :
2023

Abstract

Myeloproliferative neoplasms (MPNs) with concurrent BCR‐ABL1 fusion gene and CALR mutation are especially rare. We report a patient with coexisting BCR‐ABL1 fusion gene, CALR, and TET2 mutations who was treated with the combination of the second‐generation TKI nilotinib and JAK1/JAK2 inhibitor ruxolitinib. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20500904
Volume :
11
Issue :
1
Database :
Complementary Index
Journal :
Clinical Case Reports
Publication Type :
Academic Journal
Accession number :
161548503
Full Text :
https://doi.org/10.1002/ccr3.6801