Fibrostenotic eosinophilic esophagitis phenotype is defined by a proliferative gene signature.

As seen, expression of non-fs EoE is intermediate between FS-EoE and controls in these examples regardless if statistically different between FS-EoE and non-fs EoE or not. Approximately 90% of the DEGs identified between FS-EoE versus control follow a pattern in which non-fs EoE has expression intermediate between controls and FS EoE. Eosinophilic Esophagitis (EoE) is a chronic inflammatory esophageal disease in which a subset of patients undergo pathologic tissue remodeling. [Extracted from the article]