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Leydig cell hyperplasia of ovary – An unusual finding in postneoadjuvant chemotherapy case of primary fallopian tube carcinoma.
- Source :
- Journal of Mid-life Health; Jul-Sep2022, Vol. 13 Issue 3, p247-250, 4p
- Publication Year :
- 2022
-
Abstract
- A large number of high-grade serous ovarian carcinomas originate in the fallopian tubes. Neoadjuvant chemotherapy followed by surgery may lead to a number of chemotherapy-induced changes in the ovary, which may lead to an erroneous diagnosis. We present a rare case of a 55-year-old postmenopausal woman who was clinically diagnosed with carcinoma of the right ovary; on histopathologic evaluation after neoadjuvant chemotherapy, the primary site was found to be the right fallopian tube. The right ovary showed chemotherapy-related changes along with extensive Leydig cell hyperplasia. As the presence of Leydig cell hyperplasia in this setting is an unusual finding, it may pose a diagnostic dilemma for the pathologist; so an awareness of this entity is important to avoid misdiagnosis. [ABSTRACT FROM AUTHOR]
- Subjects :
- LEYDIG cells
FALLOPIAN tubes
OVARIES
HYPERPLASIA
NEOADJUVANT chemotherapy
Subjects
Details
- Language :
- English
- ISSN :
- 09767800
- Volume :
- 13
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Mid-life Health
- Publication Type :
- Academic Journal
- Accession number :
- 161520309
- Full Text :
- https://doi.org/10.4103/jmh.jmh_117_22