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N6‐methyladenine profiling of low‐input multiplex clinical samples on transcriptome reveals RNA modifications implicated in type 2 diabetes and acute myocardial infarction.
- Source :
- Clinical & Translational Medicine; Jan2023, Vol. 13 Issue 1, p1-6, 6p
- Publication Year :
- 2023
-
Abstract
- (A) The expression of the FTO gene shows significant down-regulation in patients with T2D+AMI, relative to patients with T2D (***p < 0.001). N<superscript>6</superscript>-methyladenine profiling of low-input multiplex clinical samples on transcriptome reveals RNA modifications implicated in type 2 diabetes and acute myocardial infarction (J) The volcano plot shows m6A enriched genes in T2D+AMI samples and T2D samples. (H) The histogram shows a globally higher m6A modification level in patients with T2D+AMI, relative to patients with T2D. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 20011326
- Volume :
- 13
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Clinical & Translational Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 161472286
- Full Text :
- https://doi.org/10.1002/ctm2.1165