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N6‐methyladenine profiling of low‐input multiplex clinical samples on transcriptome reveals RNA modifications implicated in type 2 diabetes and acute myocardial infarction.

Authors :
Qin, Shanshan
Yang, Kun
Han, Shaoqing
Yuan, Yushu
Mo, Jing
Xiao, Mengyao
Yang, Yin
Wang, Yafen
Fang, Xin
Wang, Fang
Zhang, Wei
Liu, Song‐Mei
Weng, Xiaocheng
Zhou, Xiang
Source :
Clinical & Translational Medicine; Jan2023, Vol. 13 Issue 1, p1-6, 6p
Publication Year :
2023

Abstract

(A) The expression of the FTO gene shows significant down-regulation in patients with T2D+AMI, relative to patients with T2D (***p < 0.001). N<superscript>6</superscript>-methyladenine profiling of low-input multiplex clinical samples on transcriptome reveals RNA modifications implicated in type 2 diabetes and acute myocardial infarction (J) The volcano plot shows m6A enriched genes in T2D+AMI samples and T2D samples. (H) The histogram shows a globally higher m6A modification level in patients with T2D+AMI, relative to patients with T2D. [Extracted from the article]

Details

Language :
English
ISSN :
20011326
Volume :
13
Issue :
1
Database :
Complementary Index
Journal :
Clinical & Translational Medicine
Publication Type :
Academic Journal
Accession number :
161472286
Full Text :
https://doi.org/10.1002/ctm2.1165