Transition‐metal‐free Synthesis of tetra‐substituted Vinyl Iodides by Cascade Sequential Reaction of α‐Keto Acids, 1‐Iodoalkynes, and Alkyl Halides.

The cascade sequential reaction of α‐keto acids, 1‐iodoalkynes, and alkyl halides are reported herein to synthesize tetra‐substituted vinyl iodides. It represents an efficient protocol to access a diverse range of tetra‐substituted vinyl iodides starting from simple materials in a one‐pot fashion, featuring mild reaction conditions, ease of operation, and broad substrate scope. [ABSTRACT FROM AUTHOR]