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Expression Pattern of a New Marker, Gl7 in Different Stages of B-Cell Maturation and Its Utility in B-Lymphoblastic Leukemia/Lymphoma Measurable Residual Disease Assessment.

Authors :
Varghese, S. S.
Sriram, H.
Chatterjee, G.
Girase, K.
Rajpal, S.
Ghogale, S.
Deshpande, N.
Badrinath, Y.
Patkar, N. V.
Gujral, S.
Subramanian, P. G.
Tembhare, P.
Source :
Indian Journal of Medical & Paediatric Oncology; 2022 Supplement, Vol. 43, pS1-S19, 19p
Publication Year :
2022

Abstract

Correspondence to: docprt@gmail.com I Background: i Increasing use of targeted therapies such as anti-CD19 Blinatumomab/CAR-T-cells and anti-CD20 rituximab obviates the need for additional B-cell maturation-associated markers to evaluate deviation from normal in bone marrow (BM) in patients with B-lymphoblastic leukemia/lymphoma (B-ALL) by multicolor flow cytometry (MFC). I Conclusion: i GL7 appears in B-cell maturation in BM at late BCP2 stage and is expressed in a proportion of B-ALL patients. [Extracted from the article]

Subjects

Subjects :
LEUKEMIA
LYMPHOMAS
BONE marrow

Details

Language :
English
ISSN :
09715851
Volume :
43
Database :
Complementary Index
Journal :
Indian Journal of Medical & Paediatric Oncology
Publication Type :
Academic Journal
Accession number :
161340138
Full Text :
https://doi.org/10.1055/s-0042-1755519