Screening children for presymptomatic type 1 diabetes.

Type 1 diabetes (T1D) is one of the commonest chronic conditions of childhood.[1] The pathophysiology of T1D comprises four stages of which the first two are presymptomatic and hallmarked by autoantibodies, and the last two are accompanied by hyperglycaemia. This analysis article will provide the rationale for screening, give an overview of the international screening landscape, discuss the benefits and risks of screening children for T1D, and examine the impact of screening on general practice. RISKS FROM T1D SCREENING The National Screening Committee recognise that no screening programme is without harm, and we need to gain further understanding of the impact of T1D screening on families. T1D screening status: an outline of the advantages and potential risks or harms of paediatric general population T1D screening. [Extracted from the article]