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T-Cell Responses Against Mycobacterium ulcerans and Mycobacterium tuberculosis Protein Extracts Identify Children With Buruli Ulcer Disease.
- Source :
- Journal of the Pediatric Infectious Diseases Society; Dec2022, Vol. 11 Issue 12, p575-577, 3p
- Publication Year :
- 2022
-
Abstract
- Immune-based diagnosis of Buruli ulcer disease (BUD) in children is difficult due to cross-reactivity between mycobacteria. We found that T-cell IFNγ/TNFα responses against Mycobacterium (M.) ulcerans and M. tuberculosis (PPD<subscript>Mulc</subscript>, PPD<subscript>Mtub</subscript>) were different between children with BUD (n = 27) and TB (n = 20) but only ratios (PPD<subscript>Mtub</subscript>/PPD<subscript>Mulc</subscript>) discriminated the study groups efficiently. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20487193
- Volume :
- 11
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Journal of the Pediatric Infectious Diseases Society
- Publication Type :
- Academic Journal
- Accession number :
- 161035171
- Full Text :
- https://doi.org/10.1093/jpids/piac092