Role of Magnetic Resonance Imaging (MRI) in the Etiological Diagnosis of Neonatal Seizures: A Prospective Observational Study.

MRI-based diagnosis - wherein the etiology was established primarily based on the MRI - was seen in 26 (36.7%) neonates: viral encephalitis (12), perinatal stroke (8), intracranial hemorrhage (3) and CNS malformations (3). Most neonatal seizures are acute-provoked, and the common etiologies are hypoxic-ischemic encephalopathy (HIE), stroke, central nervous system (CNS) infections, CNS malformations, and inborn errors of metabolism (IEM).[[1]],[[2]] Diagnosis of the underlying etiology of seizures is essential for appropriate management and prediction of neurodevelopmental outcomes. In this prospective observational study, we assessed the role of magnetic resonance imaging (MRI) in identifying the etiology of neonatal seizures and analyzed the spectrum of brain lesions identified by MRI. [Extracted from the article]