Development of GelMA ink for multi-scale biological 3D printing.

More and more advanced technologies are applied to improve the therapy quality with the unceasingof the technical progress. Bio-printing has become one of the most microfabrication methods which could be used in the fields of craniofacial transplantation, crown and tooth repair, prosthetic devices, medical equipment, organ printing, bold tissue engineering scaffold and so on. However, most of the existing bio-ink materials could have the disadvantages of poor conductivity. To solve this problem, several ways of optimizing and improving the bio-ink formula will be proposed, including electric field assisted bioprinting of cell-loaded GelMA microspheres, nano-clay-assisted 3D printing of complex bio hydrogel scaffolds, biological 3D printing with fiber microspheres, using new materials such as MC/Gelma with high shape integrity and applying HGSM in bioprinting to improve the overall properties of the product. And in this paper, GelMA ink is used as the basic material for subsequent research so that the problem of how to construct highly bioactive tissue structure to realize printing structure functionalization can be solved to some extent. [ABSTRACT FROM AUTHOR]