A double‐hit model reveals individual and synergic consequences of prenatal and adolescent postnatal ethanol exposure.

In the article, the authors discuss how prenatal ethanol alcohol (EtOH) exposure (PEE) can be used as a sign of EtOH involvement among adolescent people. Also cited are the association of PEE with various neuropsychological deficits and mental disorders like fetal alcohol spectrum disorders (FASD), mental retardation, and autism spectrum disorder, the generator of alcoholism hypothesis, and the double hit exposure protocols.