Evaluation of the Correlation Between Stool Antigen Test and Histopathology Report Results of Helicobacter pylori Presence in Near East University Hospital Applicants .

Introduction: Helicobacter pylori infects approximately half of the population worldwide. In our study, we aimed to investigate the correlation between the faeces antigen rapid test, which is one of the methods used in the diagnosis of H. pylori, and those with a positive diagnosis of H. pylori obtained from histopathological examination reports on stomach biopsy specimens. Materials and Methods: This study included 1,227 patients who applied to the Near East University Hospital between January 1, 2017 and December 31, 2019 and were examined with a H. pylori antigen rapid test in the microbiology laboratory. The patients’ age, gender, complaints and diagnosis were obtained by retrospective examination of H. pylori antigen test in human faecal specimens results and histopathology reports. Results: It was determined that 67 (5.5%) of 1,227 patients whose stool H. pylori antigen rapid test were examined were H. pylori positive. Biopsy was performed in 344 (28%) of the patients, and according to histopathology reports, 84 (24.4%) of the patients who underwent biopsy were found to be H. pylori positive. Conclusion: The sensitivity of H. pylori antigen rapid test in faecal specimens was 79.7% and the specificity was 100%. In our study, in which the results were evaluated retrospectively, it was concluded that the H. pylori stool Ag test may use in the detection of H. pylori and infection because it was non-invasive, cheap, easily applicable and gave positive results close to histopathological results. [ABSTRACT FROM AUTHOR]