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Pancreatic Secretion in Man: Effect of Fasting, Drugs, Pancreatic Enzymes, and Somatostatin.
- Source :
- American Journal of Gastroenterology (Springer Nature); Feb1994, Vol. 89 Issue 2, p267-270, 4p, 3 Graphs
- Publication Year :
- 1994
-
Abstract
- The inhibitory effect of different drugs on pancreatic secretions was assessed in a patient with a posttraumatic pancreatic-cutaneous fistula. The various drugs examined were: pancreatic enzymes, competition, verapamil, propantheline, acetazolamide, and somatostatin analog octreotide. Only fasting and octreotide reduced pancreatic secretion. The optimum dose of octreotide was 50 μg bid given subcutaneously; increasing the dose up to 100 μg tid had no additional benefit. A stable pancreatic-cutaneous fistula is an excellent model to assess the effect of different therapeutic measures on pancreatic secretion. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00029270
- Volume :
- 89
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- American Journal of Gastroenterology (Springer Nature)
- Publication Type :
- Academic Journal
- Accession number :
- 16061591