Back to Search
Start Over
Can individual fatty acids be used as functional biomarkers of dairy fat consumption in relation to cardiometabolic health? A narrative review.
- Source :
- British Journal of Nutrition; 12/28/2022, Vol. 128 Issue 12, p2373-2386, 14p
- Publication Year :
- 2022
-
Abstract
- In epidemiological studies, dairy food consumption has been associated with minimal effect or decreased risk of some cardiometabolic diseases (CMD). However, current methods of dietary assessment do not provide objective and accurate measures of food intakes. Thus, the identification of valid and reliable biomarkers of dairy product intake is an important challenge to best determine the relationship between dairy consumption and health status. This review investigated potential biomarkers of dairy fat consumption, such as odd-chain, trans- and branched-chain fatty acids (FA), which may improve the assessment of full-fat dairy product consumption. Overall, the current use of serum/plasma FA as biomarkers of dairy fat consumption is mostly based on observational evidence, with a lack of well-controlled, dose–response intervention studies to accurately assess the strength of the relationship. Circulating odd-chain SFA and trans-palmitoleic acid are increasingly studied in relation to CMD risk and seem to be consistently associated with a reduced risk of type 2 diabetes in prospective cohort studies. However, associations with CVD are less clear. Overall, adding less studied FA such as vaccenic and phytanic acids to the current available evidence may provide a more complete assessment of dairy fat intake and minimise potential confounding from endogenous synthesis. Finally, the current evidence base on the direct effect of dairy fatty acids on established biomarkers of CMD risk (e.g. fasting lipid profiles and markers of glycaemic control) mostly derives from cross-sectional, animal and in vitro studies and should be strengthened by well-controlled human intervention studies. [ABSTRACT FROM AUTHOR]
- Subjects :
- CARDIOVASCULAR disease related mortality
BIOMARKERS
CARDIOVASCULAR diseases risk factors
NUTRITIONAL assessment
SERUM
BLOOD plasma
GLYCEMIC control
GUT microbiome
HEALTH status indicators
DAIRY products
TYPE 2 diabetes
METABOLIC disorders
RISK assessment
METABOLIC syndrome
MOLECULAR structure
FATTY acids
DIETARY fats
SHORT-chain fatty acids
Subjects
Details
- Language :
- English
- ISSN :
- 00071145
- Volume :
- 128
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- British Journal of Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 160534405
- Full Text :
- https://doi.org/10.1017/S0007114522000289