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Long‐term normothermic perfusion of human livers for longer than 12 days.

Authors :
Lau, Ngee‐Soon
Ly, Mark
Dennis, Claude
Liu, Ken
Kench, James
Crawford, Michael
Pulitano, Carlo
Source :
Artificial Organs; Dec2022, Vol. 46 Issue 12, p2504-2510, 7p
Publication Year :
2022

Abstract

[Color figure can be viewed at wileyonlinelibrary.com] gl GLO:FQJ/01dec22:aor14372-fig-0003.jpg PHOTO (COLOR): 3 Evidence of worsening liver function at the end of perfusion during long-term ex situ machine perfusion of human livers. Keywords: ex situ machine perfusion; long-term perfusion; split livers EN ex situ machine perfusion long-term perfusion split livers 2504 2510 7 11/17/22 20221201 NES 221201 In this case report, we preserved human livers for up to 13 days under normothermic conditions using a modified commercial perfusion system. (A and B) For all livers (A: Liver 1, B: Liver 2) and all partial grafts, perfusate glucose levels remained stable during long-term perfusion sustained on infusions of glucose and glucagon. Long-term perfusion, ex situ machine perfusion, split livers. [Extracted from the article]

Subjects

Subjects :
REPERFUSION
PERFUSION
LIVER

Details

Language :
English
ISSN :
0160564X
Volume :
46
Issue :
12
Database :
Complementary Index
Journal :
Artificial Organs
Publication Type :
Academic Journal
Accession number :
160233551
Full Text :
https://doi.org/10.1111/aor.14372