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Seroprevalence of Measles Antibodies in a Highly MMR-Vaccinated Population.
- Source :
- Vaccines; Nov2022, Vol. 10 Issue 11, p1859, 8p
- Publication Year :
- 2022
-
Abstract
- As an extremely contagious pathogen, a high rate of vaccine coverage and the durability of vaccine-induced immunity are key factors to control and eliminate measles. Herein, we assessed the seroprevalence of antibodies specific to measles in a cohort of 1393 adults (20–44 years old). ELISA results showed a nontrivial proportion of 37.6% study subjects being negative for measles immunoglobulin G (IgG). We also found significant influences of sex and age of the study cohort on the IgG level. Our findings suggest that even within a highly vaccinated population, a subset of individuals may still have sub-optimal immunity against measles and potentially be susceptible during any future measles outbreaks. [ABSTRACT FROM AUTHOR]
- Subjects :
- MEASLES
IMMUNOGLOBULIN G
SEROPREVALENCE
IMMUNOGLOBULINS
VACCINATION coverage
Subjects
Details
- Language :
- English
- ISSN :
- 2076393X
- Volume :
- 10
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Vaccines
- Publication Type :
- Academic Journal
- Accession number :
- 160207047
- Full Text :
- https://doi.org/10.3390/vaccines10111859