FORMATION, SPECTRAL CHARACTERIZATION AND BIOLOGICAL STUDY FOR METAL COMPLEXES DERIVED FROM DITHIOCARBAMATE WITH SCHIFF-BASE LIGAND.

The synthesis of a new mixed Schiff-base and DTCs ligands and its metal complexes are reported. Schiff-base was prepared by reaction of ((E)-2-amino-6-(pyridin-2-yl diazenyl)phenol) with 4-(dimethylamino)benzaldehyde). The complexes were prepared by mixing the (2-(((E)-4-(dimethylamino)benzylidene)amino)-6-((E)-pyridin-2-yldiazenyl)phenol) ligand (HL) and (potassium diphenylcarbamodithioate) ligand (L) with the metal salts; Cobalt(II), Nickel(II), Zinc(II) and Cadmium(II) in a 1:1:1 mole ratio. Physico-chemical techniques were implemented, as required, to characterise the ligands and complexes. These include; elemental microanalysis, Fourier Transform Infrared Spectra, Electronic spectra and 1H-Nuclear magnetic resonance spectroscopy, chloride content, magnetic susceptibility and conductance. Thermal stability (TGA-DSC) of the ligand and selected complexes were also investigated. These analyses revealed the isolation of six and four coordinate structures in the solid and solution sate. The antimicrobial activity of the ligand and its complexes against bacterial strains species was examined. [ABSTRACT FROM AUTHOR]