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bMSAF is a prognostic predictor for advanced hepatocellular carcinoma patients treated with immune checkpoint inhibitor camrelizumab and antiā€angiogenic agent apatinib combination therapy.

Authors :
Xu, Gehan
Cui, Liang
Li, Jin
Wang, Quanren
Li, Pansong
Xia, Xuefeng
Yi, Xin
Guan, Quanlin
Xu, Jianming
Source :
Clinical & Translational Medicine; Oct2022, Vol. 12 Issue 10, p1-6, 6p
Publication Year :
2022

Abstract

In total patients, low bTMB (bTMB-L, optimal cutoff = 4) showed significantly longer OS ( I p i = .019) compared with high bTMB (bTMB-H) (Figure 1A and B), and bTMB was significantly associated with disease control rate (DCR) (Figure 1C and D), but not objective response rate (ORR) (Supplementary Figure S4A). Patients with bMSAF-H and bTMB-H (n = 11) are indicated in red, patients with bMSAF-L and bTMB-H (n = 21) are indicated in blue, and those with bMSAF-L and bTMB-L (n = 10) are indicated in green. BMSAF is a prognostic predictor for advanced hepatocellular carcinoma patients treated with immune checkpoint inhibitor camrelizumab and anti-angiogenic agent apatinib combination therapy. [Extracted from the article]

Details

Language :
English
ISSN :
20011326
Volume :
12
Issue :
10
Database :
Complementary Index
Journal :
Clinical & Translational Medicine
Publication Type :
Academic Journal
Accession number :
160149483
Full Text :
https://doi.org/10.1002/ctm2.1086