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Prognostic factors in the treatment of gastric mucosal atypical hyperplasia by endoscopic submucosal dissection.

Authors :
Hong, Yongping
Chen, Xingxing
Li, Guofeng
Source :
BMC Surgery; 11/7/2022, Vol. 22 Issue 1, p1-6, 6p
Publication Year :
2022

Abstract

<bold>Background: </bold>Endoscopic submucosal dissection (ESD) is becoming increasingly popular as a treatment for precancerous lesions and early cancers of the stomach. However, there have been few studies on the factors associated with the recurrence of precancerous lesions after ESD.<bold>Methods: </bold>To investigate the prognostic factors of gastric intraepithelial neoplasia, we retrospectively analyzed 115 patients who were treated with ESD between February 2018 and January 2020. Chi-square test and Fisher's extract test were used to select factors for further investigation, and prognostic analysis was carried out with the Kaplan-Meier method and a Cox regression model.<bold>Results: </bold>Platelet counts (Pā€‰=ā€‰0.027) and albumin levels (Pā€‰=ā€‰0.011) were both lower in patients with recurrence than in patients without recurrence of gastric mucosal atypical hyperplasia after ESD.<bold>Conclusions: </bold>This study reveals that low platelet counts and albumin levels were probably unfavorable prognostic factors in mucosal atypical hyperplasia of the stomach. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712482
Volume :
22
Issue :
1
Database :
Complementary Index
Journal :
BMC Surgery
Publication Type :
Academic Journal
Accession number :
160071231
Full Text :
https://doi.org/10.1186/s12893-022-01832-4