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Novel chlorine‐extending polymer coating with prolonged antiviral activity against SARS‐CoV‐2.

Authors :
Zhang, Y.
Choi, Y. W.
Demir, B.
Ekbataniamiri, F.
Fulton, M. L.
Ma, M.
Schang, L. M.
Purevdorj‐Gage, L.
Qiao, M.
Source :
Letters in Applied Microbiology; Nov2022, Vol. 75 Issue 5, p1346-1353, 8p
Publication Year :
2022

Abstract

We previously reported a novel polymeric surface coating, namely, HaloFilm™ that can immobilize and extend the antimicrobial activity of chlorine on surfaces. In this study, we demonstrated the continuous antiviral efficacy of HaloFilm when applied on stainless steel and cotton gauze as two representative models for non‐porous and porous surfaces against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Forty‐eight hours post HaloFilm application and chlorination and 2 h post the viral challenge, the inoculum titre was reduced by 2.25 ± 0.33 and ≥4.36 ± 0.23 log10 TCID50 on non‐porous and porous surfaces, respectively. The half‐life of the virus was shorter (13.86 min) on a HaloFilm‐coated surface than what has been reported on copper (46.44 min). [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
SARS-CoV-2

Details

Language :
English
ISSN :
02668254
Volume :
75
Issue :
5
Database :
Complementary Index
Journal :
Letters in Applied Microbiology
Publication Type :
Academic Journal
Accession number :
159940498
Full Text :
https://doi.org/10.1111/lam.13804