Evaluation of the Antimicrobial Resistance Rates in Urine Samples of the Elderly.

Objective: Urinary tract infections (UTIs) are common in the community. The prevalence of UTIs rises in the elderly as a result of age-related changes and comorbidities. In treating the elderly, it is important to choose antibiotics carefully and avoid unnecessary ones. The goal of this study was to analyze the bacteria isolated from geriatric urine samples and their resistance patterns. Materials and Methods: Urine culture results in geriatric patients (>65 years old) were analyzed between January 1, 2016 and February 1, 2020. Antibiotic resistance was evaluated in frequently isolated bacteria. In terms of antibiotic resistance, antibiotics that can be used in outpatient therapy and do not require the approval of an infectious disease specialist were investigated. Results: The records of 37735 urinary samples were screened. In 31.3% (11840/37735) of the urine culture microorganisms were isolated. Escherichia coli was the most common microorganism with a rate of 40.1% (4758/11840), followed by Klebsiella spp. with 15.5% (1844/11840), Enterococcus spp. with 10.3% (1222/11840), and Pseudomonas aeruginosa with 3.4% (406/11840). Ceftriaxone resistance of 37.6% was found in Escherichia coli; ciprofloxacin resistance was 41.5%, trimethoprim-sulfamethoxazole (TMP-SMX) resistance was 43.4%, and nitrofurantoin resistance was 1%. There was no resistance to fosfomycin. The antibiotic resistance of Klebsiella spp. gave a result of 41.6% ceftriaxone resistance, while ciprofloxacin resistance was 32.6%, and TMP-SMX resistance was 39.6%. The antibiotic resistance of Pseudomonas aeruginosa was 19.04% ciprofloxacin resistance, and 5.1% amikacin resistance. In Enterococcus spp. ampicillin resistance was found to be 42.9%. Conclusion: Infections in geriatric patients can quickly prove fatal. Antibiotic selection is critical in regard to elderly patients, and knowing regional antimicrobial resistance patterns is important. But balancing efficacy, safety, and tolerability with the development of antimicrobial resistance in this patient population is difficult. [ABSTRACT FROM AUTHOR]