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Transplantation provides superior survival high risk myeloid malignancies in older patients.

Authors :
Ustun, Celalettin
Warlick, Erica
Nathan, Sunita
Burns, Linda J.
Weisdorf, Daniel
Source :
Leukemia & Lymphoma; Oct2022, Vol. 63 Issue 10, p2494-2498, 5p
Publication Year :
2022

Abstract

Transplant Referral Patterns for Patients (Pts) with Newly Diagnosed (ND) Higher-Risk (HR) Myelodysplastic Syndromes (MDS), and European Leukemianet (ELN) 2010 Intermediate-Risk (IR) or Adverse-Risk (AR) Acute Myeloid Leukemia (AML) in the Connect® MDS/AML Registry Transplant Cell Ther. Disease-free survival in patients with MDS (A, reported by Nakamura et al. [[3]]) and patients with AML (B, reported by Ustun et al. [[5]]) is superior after allogeneic hematopoietic cell transplantation compared with no transplantation. In older patients with acute myeloid leukemia (AML) or higher-risk myelodysplastic syndrome (MDS), reluctance to refer patients for consideration of allogeneic hematopoietic stem cell transplantation (alloHCT) still remains in some spheres. [Extracted from the article]

Details

Language :
English
ISSN :
10428194
Volume :
63
Issue :
10
Database :
Complementary Index
Journal :
Leukemia & Lymphoma
Publication Type :
Academic Journal
Accession number :
159584056
Full Text :
https://doi.org/10.1080/10428194.2022.2076851