THE EFFECT OF <em>BORDETELLA PERTUSSIS</em> VACCINE ON THE DEVELOPMENT OF EXPERIMENTAL THYROIDITIS IN RATS IMMUNIZED BY THE INTRA-LYMPH NODE ROUTE OR INTO A HIND FOOTPAD.

The article examines the effect of Bordetella pertussis vaccine on the development of experimental thyroiditis in rats immunized by the intra-lymph node route or into a hind footpad. Pertussis vaccine has been shown to have an enhancing effect on the development of experimental autoallergic diseases in laboratory animals. The results indicate that moderate to severe thyroiditis may be established within 8 days with the production of circulating thyroglobulin antibody but not thyroid complement fixing antibody.