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Intrahippocampal co-administration of nicotine and O-acetyl-L-carnitine prevents the H-89-induced spatial learning deficits in Morris water maze.
- Source :
- Journal of Complementary & Integrative Medicine; Sep2022, Vol. 19 Issue 3, p691-696, 6p
- Publication Year :
- 2022
-
Abstract
- The article highlights a study on the protective effects of nicotine and O-acetyl-L-carnitine against H89-induced spatial memory deficits. It discusses that the potential synergistic effects of nicotine and O-acetyl-L-carnitine in preventing protein kinase AII inhibitor (H-89)-induced spatial learning impairments.
- Subjects :
- STATISTICS
STATISTICAL significance
CARNITINE
HIPPOCAMPUS (Brain)
COMBINATION drug therapy
ANALYSIS of variance
CONNECTIVE tissue growth factor
ANIMAL experimentation
PROTEIN kinase inhibitors
NICOTINE
STEREOTAXIC techniques
RATS
T-test (Statistics)
OXIDATIVE stress
MEMORY disorders
LEARNING disabilities
DATA analysis
TRANSCRIPTION factors
SPACE perception
ACETYLTRANSFERASES
Subjects
Details
- Language :
- English
- ISSN :
- 15533840
- Volume :
- 19
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Complementary & Integrative Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 159417899
- Full Text :
- https://doi.org/10.1515/jcim-2021-0035