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A new steroidal saponin from the aerial parts of Solanum torvum.

Authors :
Viet Cuong, Le Canh
Nhi, Nguyen Phuc Khanh
Ha, Tran Phuong
Anh, Le Tuan
Dat, Ton That Huu
Oanh, Phung Thi Thuy
Phuong, Nguyen Thi Minh
Thu, Vo Thi Kim
Duc, Ho Viet
Anh, Hoang Le Tuan
Source :
Natural Product Research; Oct2022, Vol. 36 Issue 19, p4892-4897, 6p
Publication Year :
2022

Abstract

A new steroidal saponin, torvoside R (1), was isolated along with torvoside Q (2) and macaoside (3) from dichloromethane soluble-portion of the aerial parts of Solanum torvum. Their chemical structures were elucidated using HRESIMS, 1 D- and 2 D-NMR as well as comparison with those reported in the literature. All isolated compounds (1 − 3) exhibited cytotoxicity against SK-LU-1, HepG2, MCF-7, and T24 cancer cell lines with IC<subscript>50</subscript> values ranging from 14.18 to 89.31 µg/mL. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14786419
Volume :
36
Issue :
19
Database :
Complementary Index
Journal :
Natural Product Research
Publication Type :
Academic Journal
Accession number :
159325565
Full Text :
https://doi.org/10.1080/14786419.2021.1908282