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A novel furo[3,2-c]pyridine-based AIE photosensitizer for specific imaging and photodynamic ablation of Gram-positive bacteria.
- Source :
- Chemical Communications; 9/21/2022, Vol. 58 Issue 74, p10392-10395, 4p
- Publication Year :
- 2022
-
Abstract
- An Rh-catalyzed tandem reaction was performed to construct an AIE-active furo[2,3-c]pyridine-based photosensitizer, named LIQ-TF. LIQ-TF showed near-infrared emission with high quantum yield, and high <superscript>1</superscript>O<subscript>2</subscript> and ˙OH generation efficiency, and could be used for specific imaging and photodynamic ablation of Gram-positive bacteria in vitro and in vivo, showing great potential for combating multiple drug-resistant bacteria. [ABSTRACT FROM AUTHOR]
- Subjects :
- GRAM-positive bacteria
PHOTOSENSITIZERS
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 58
- Issue :
- 74
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 159132761
- Full Text :
- https://doi.org/10.1039/d2cc04084k